Archive for July, 2015

Researchers Develop Model to Predict Wound Healing Success

Tuesday, July 28th, 2015

A team of military and civilian researchers has developed a way to make predictions about wound healing that could help surgeons make critical decisions, such as when to close a wound. This information could minimize complications for traumatically injured patients, as both premature and late closing can lead to serious problems for the patient.

Using advanced computer analytics and looking for patterns of inflammation, the team from the USU Walter Reed Surgical Critical Care Initiative analyzed biomarker data in collected samples of blood and tissue, as well as clinical observations to predict the likelihood of wound failure.

“This study demonstrates that it is not merely the physical destructive nature related to the mechanism of injury in wounds, but the (body’s) resulting inflammatory response, that dictates wound outcome,” says the senior author, Navy Capt. (Dr.) Eric Elster, in a press release. Dr. Elster is professor and chair of the Department of Surgery at the Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center. He is also a member of the Board of Directors of the National Trauma Institute.

Elster points out that the response is similar in both military and civilian patients, allowing for a translation between patient populations.

The study, ”Lessons of War: Turning Data into Decisions,” was published online July 17, 2015 in the journal E-Biomedicine.